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Symbol
Name
ID

Kmt2e
lysine (K)-specific methyltransferase 2E
MGI:1924825

Phenotype annotations related to immune system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Mouse Phenotypes

immune system phenotype

abnormal granulocyte differentiation

abnormal neutrophil differentiation

small thymus

thymus hypoplasia

decreased thymocyte number

abnormal lymphopoiesis

decreased pro-B cell number

decreased double-negative T cell number

decreased double-positive T cell number

increased neutrophil cell number

decreased B cell number

decreased pre-B cell number

decreased NK cell number

decreased NK T cell number

decreased T cell number

decreased macrophage cell number

decreased leukocyte cell number

small spleen

spleen hypoplasia

abnormal neutrophil physiology

small lymph nodes

blepharitis

increased susceptibility to bacterial infection

Availability

Mouse Genotype

Kmt2e^tm1.1Hjf/Kmt2e^tm1.1Hjf

*

Kmt2e^tm1Apa/Kmt2e^tm1Apa

Kmt2e^tm1Nik/Kmt2e^tm1Nik

Kmt2e^tm1.1Hjf/Kmt2e⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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